人 FCGR2B (NM_004001) cDNA克隆

Accession: NM_004001
基因名称: FCGR2B
基因别名: CD32; FCG2; CD32B; FCGR2; IGFR2
基因描述: Homo sapiens Fc fragment of IgG, low affinity IIb, receptor (CD32) (FCGR2B), transcript variant 1, mRNA.
种属: Human
CDS区长度: 933 (查看编码区序列)
翻译后氨基酸长度: 310 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
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G109514 人 FCGR2B (NM_004001) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]