人 CXCR4 (NM_001008540) cDNA克隆

Accession: NM_001008540
基因名称: CXCR4
基因别名: FB22; HM89; LAP3; LCR1; NPYR; WHIM; CD184; LESTR; NPY3R; NPYRL; HSY3RR; NPYY3R; D2S201E
基因描述: Homo sapiens chemokine (C-X-C motif) receptor 4 (CXCR4), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1071 (查看编码区序列)
翻译后氨基酸长度: 356 (查看氨基酸序列)
Transcript Variant: This variant (1), also known as CXCR4-Lo, represents the longer transcript and encodes the longer isoform (a).
产品编号 产品名称 载体 规格 价格
G110138 人 CXCR4 (NM_001008540) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]