人 MTHFD1L (NM_001242769) cDNA克隆

基本信息

Accession: NM_001242769
基因名称: MTHFD1L
基因别名: FTHFSDC1; MTC1THFS; dJ292B18.2; RP1-292B18.2
基因描述: Homo sapiens methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like (MTHFD1L), transcript variant 4, mRNA.
种属: Human
CDS区长度: 828 (查看编码区序列)
翻译后氨基酸长度: 275 (查看氨基酸序列)
Transcript Variant: This variant (4) differs in the 3' UTR and coding sequence and uses an alternate in-frame splice junction at the 5' end of an exon compared to variant 1. The resulting isoform (4) has a shorter and distinct C-terminus and lacks a single internal aa compared to isoform 1. Isoform 4 is thought to lack THF synthase activity.

订购信息

产品编号 产品名称 载体 规格 价格
G110298 人 MTHFD1L (NM_001242769) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 MTHFD1L (NM_001242767) cDNA克隆 transcript variant 1
人 MTHFD1L (NM_015440) cDNA克隆 transcript variant 2
人 MTHFD1L (NM_001242768) cDNA克隆 transcript variant 3
人 MTHFD1L (NM_001242769) cDNA克隆 transcript variant 4

基因简介

The protein encoded by this gene is involved in the synthesis of tetrahydrofolate (THF) in the mitochondrion. THF is important in the de novo synthesis of purines and thymidylate and in the regeneration of methionine from homocysteine. Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jun 2011]

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