人 LILRA3 (NM_001172654) cDNA克隆

基本信息

Accession: NM_001172654
基因名称: LILRA3
基因别名: e3; HM31; HM43; ILT6; LIR4; CD85E; ILT-6; LIR-4
基因描述: Homo sapiens leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3 (LILRA3), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1128 (查看编码区序列)
翻译后氨基酸长度: 375 (查看氨基酸序列)
Transcript Variant: This variant (2) uses an alternate in-frame splice site in the central coding region, compared to variant 1. The resulting isoform (2) lacks an internal segment, compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G111036 人 LILRA3 (NM_001172654) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 LILRA3 (NM_006865) cDNA克隆 transcript variant 1
人 LILRA3 (NM_001172654) cDNA克隆 transcript variant 2

基因简介

Leukocyte Ig-like receptors (LIRs) are a family of immunoreceptors expressed predominantly on monocytes and B cells and at lower levels on dendritic cells and natural killer (NK) cells. All LIRs in subfamily B have an inhibitory function (see, e.g., LILRB1, MIM 604811). LIRs in subfamily A, with short cytoplasmic domains lacking an immunoreceptor tyrosine-based inhibitory motif (ITIM) and with transmembrane regions containing a charged arginine residue, may initiate stimulatory cascades (see LILRA1, MIM 604810). One member of subfamily A (LILRA3) lacks a transmembrane region and is presumed to be a soluble receptor (Borges et al., 1997 [PubMed 9548455]).[supplied by OMIM, Mar 2008]

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