人 LILRA5 (NM_181985) cDNA克隆

基本信息

Accession: NM_181985
基因名称: LILRA5
基因别名: CD85; LIR9; CD85F; ILT11; LIR-9; ILT-11; LILRB7
基因描述: Homo sapiens leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5 (LILRA5), transcript variant 2, mRNA.
种属: Human
CDS区长度: 864 (查看编码区序列)
翻译后氨基酸长度: 287 (查看氨基酸序列)
Transcript Variant: This variant (2), also known as LIR9m2, lacks an in-frame coding segment, as compared to variant 1. The resulting isoform (2) lacks an internal region, as compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G149999 人 LILRA5 (NM_181985) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 LILRA5 (NM_021250) cDNA克隆 transcript variant 1
人 LILRA5 (NM_181985) cDNA克隆 transcript variant 2
人 LILRA5 (NM_181879) cDNA克隆 transcript variant 3
人 LILRA5 (NM_181986) cDNA克隆 transcript variant 4

基因简介

The protein encoded by this gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family. LIR family members are known to have activating and inibitory functions in leukocytes. Crosslink of this receptor protein on the surface of monocytes has been shown to induce calcium flux and secretion of several proinflammatory cytokines, which suggests the roles of this protein in triggering innate immune responses. This gene is one of the leukocyte receptor genes that form a gene cluster on the chromosomal region 19q13.4. Four alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]

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