人 IRF3 (NM_001197127) cDNA克隆

基本信息

Accession: NM_001197127
基因名称: IRF3
基因描述: Homo sapiens interferon regulatory factor 3 (IRF3), transcript variant 7, mRNA.
种属: Human
CDS区长度: 465 (查看编码区序列)
翻译后氨基酸长度: 154 (查看氨基酸序列)
Transcript Variant: This variant (7, also known as IRF3d) lacks a portion of the 5' coding region, and initiates translation at a downstream start codon, compared to variant 1. This variant also lacks an in-frame exon compared to variant 1. The encoded isoform (6) is shorter than isoform 1. Both variants 7 and 8 encode the same isoform (6).

订购信息

产品编号 产品名称 载体 规格 价格
G111203 人 IRF3 (NM_001197127) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 IRF3 (NM_001571) cDNA克隆 transcript variant 1
人 IRF3 (NM_001197122) cDNA克隆 transcript variant 2
人 IRF3 (NM_001197123) cDNA克隆 transcript variant 3
人 IRF3 (NM_001197124) cDNA克隆 transcript variant 4
人 IRF3 (NM_001197125) cDNA克隆 transcript variant 5
人 IRF3 (NM_001197126) cDNA克隆 transcript variant 6
人 IRF3 (NM_001197127) cDNA克隆 transcript variant 7
人 IRF3 (NM_001197128) cDNA克隆 transcript variant 8

基因简介

This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]

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