人 IRF5 (NM_001098630) cDNA克隆

基本信息

Accession: NM_001098630
基因名称: IRF5
基因别名: SLEB10
基因描述: Homo sapiens interferon regulatory factor 5 (IRF5), transcript variant 6, mRNA.
种属: Human
CDS区长度: 1497 (查看编码区序列)
翻译后氨基酸长度: 498 (查看氨基酸序列)
Transcript Variant: This variant (6) uses an alternate in-frame splice site compared to variant 5. The resulting isoform (b) lacks an internal segment, compared to isoform d. Variants 2, 3, and 6 all encode the same isoform (b).

订购信息

产品编号 产品名称 载体 规格 价格
G111747 人 IRF5 (NM_001098630) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 IRF5 (NM_002200) cDNA克隆 transcript variant 1
人 IRF5 (NM_032643) cDNA克隆 transcript variant 2
人 IRF5 (NM_001098627) cDNA克隆 transcript variant 3
人 IRF5 (NM_001098628) cDNA克隆 transcript variant 4
人 IRF5 (NM_001098629) cDNA克隆 transcript variant 5
人 IRF5 (NM_001098630) cDNA克隆 transcript variant 6
人 IRF5 (NM_001098631) cDNA克隆 transcript variant 7
人 IRF5 (NM_001242452) cDNA克隆 transcript variant 8

基因简介

This gene encodes a member of the interferon regulatory factor (IRF) family, a group of transcription factors with diverse roles, including virus-mediated activation of interferon, and modulation of cell growth, differentiation, apoptosis, and immune system activity. Members of the IRF family are characterized by a conserved N-terminal DNA-binding domain containing tryptophan (W) repeats. Multiple transcript variants encoding different isoforms have been found for this gene, and a 30-nt indel polymorphism (SNP rs60344245) can result in loss of a 10-aa segment. [provided by RefSeq, Mar 2010]

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