人 MICU1 (NM_006077) cDNA克隆

Accession: NM_006077
基因名称: MICU1
基因别名: CALC; EFHA3; CBARA1
基因描述: Homo sapiens mitochondrial calcium uptake 1 (MICU1), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1437 (查看编码区序列)
翻译后氨基酸长度: 478 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longest transcript and encodes the longest protein (isoform 1).
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G111459 人 MICU1 (NM_006077) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes an essential regulator of mitochondrial Ca2+ uptake under basal conditions. The encoded protein interacts with the mitochondrial calcium uniporter, a mitochondrial inner membrane Ca2+ channel, and is essential in preventing mitochondrial Ca2+ overload, which can cause excessive production of reactive oxygen species and cell stress. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Mar 2013]