人 MICU1 (NM_001195518) cDNA克隆

基本信息

Accession: NM_001195518
基因名称: MICU1
基因别名: CALC; EFHA3; CBARA1
基因描述: Homo sapiens mitochondrial calcium uptake 1 (MICU1), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1431 (查看编码区序列)
翻译后氨基酸长度: 476 (查看氨基酸序列)
Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 5' coding region compared to variant 1. The encoded protein (isoform 2) is shorter compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G111460 人 MICU1 (NM_001195518) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 MICU1 (NM_006077) cDNA克隆 transcript variant 1
人 MICU1 (NM_001195518) cDNA克隆 transcript variant 2
人 MICU1 (NM_001195519) cDNA克隆 transcript variant 3

基因简介

This gene encodes an essential regulator of mitochondrial Ca2+ uptake under basal conditions. The encoded protein interacts with the mitochondrial calcium uniporter, a mitochondrial inner membrane Ca2+ channel, and is essential in preventing mitochondrial Ca2+ overload, which can cause excessive production of reactive oxygen species and cell stress. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Mar 2013]

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