人 SP100 (NM_001080391) cDNA克隆

Accession: NM_001080391
基因名称: SP100
基因别名: lysp100b
基因描述: Homo sapiens SP100 nuclear antigen (SP100), transcript variant 1, mRNA.
种属: Human
CDS区长度: 2658 (查看编码区序列)
翻译后氨基酸长度: 885 (查看氨基酸序列)
Transcript Variant: This variant (1) encodes the longest isoform (1, also known as SP100C).
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G111536 人 SP100 (NM_001080391) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a subnuclear organelle and major component of the PML (promyelocytic leukemia)-SP100 nuclear bodies. PML and SP100 are covalently modified by the SUMO-1 modifier, which is considered crucial to nuclear body interactions. The encoded protein binds heterochromatin proteins and is thought to play a role in tumorigenesis, immunity, and gene regulation. Alternatively spliced variants have been identified for this gene; one of which encodes a high-mobility group protein. [provided by RefSeq, Aug 2011]