人 SP100 (NM_003113) cDNA克隆

基本信息

Accession: NM_003113
基因名称: SP100
基因别名: lysp100b
基因描述: Homo sapiens SP100 nuclear antigen (SP100), transcript variant 2, mRNA.
种属: Human
CDS区长度: 2640 (查看编码区序列)
翻译后氨基酸长度: 879 (查看氨基酸序列)
Transcript Variant: This variant (2) lacks several exons which represent the 3' coding and UTR regions of variant 1. Variant 2 represents use of an alternate transcription termination site resulting in a shorter protein (isoform 2, also known as SP100-HMG) with a distinct C-terminus. Isoform 2 is identified as a high-mobility group protein.

订购信息

产品编号 产品名称 载体 规格 价格
G111537 人 SP100 (NM_003113) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 SP100 (NM_001080391) cDNA克隆 transcript variant 1
人 SP100 (NM_003113) cDNA克隆 transcript variant 2
人 SP100 (NM_001206701) cDNA克隆 transcript variant 3
人 SP100 (NM_001206702) cDNA克隆 transcript variant 4
人 SP100 (NM_001206703) cDNA克隆 transcript variant 5
人 SP100 (NM_001206704) cDNA克隆 transcript variant 6

基因简介

This gene encodes a subnuclear organelle and major component of the PML (promyelocytic leukemia)-SP100 nuclear bodies. PML and SP100 are covalently modified by the SUMO-1 modifier, which is considered crucial to nuclear body interactions. The encoded protein binds heterochromatin proteins and is thought to play a role in tumorigenesis, immunity, and gene regulation. Alternatively spliced variants have been identified for this gene; one of which encodes a high-mobility group protein. [provided by RefSeq, Aug 2011]

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