人 TRIM22 (NM_006074) cDNA克隆

Accession: NM_006074
基因名称: TRIM22
基因别名: RNF94; STAF50; GPSTAF50
基因描述: Homo sapiens tripartite motif containing 22 (TRIM22), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1497 (查看编码区序列)
翻译后氨基酸长度: 498 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
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G111740 人 TRIM22 (NM_006074) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to the cytoplasm and its expression is induced by interferon. The protein down-regulates transcription from the HIV-1 LTR promoter region, suggesting that function of this protein may be to mediate interferon's antiviral effects. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2010]