人 GPR161 (NM_153832) cDNA克隆

Accession: NM_153832
基因名称: GPR161
基因别名: RE2
基因描述: Homo sapiens G protein-coupled receptor 161 (GPR161), transcript variant 3, mRNA.
种属: Human
CDS区长度: 1590 (查看编码区序列)
翻译后氨基酸长度: 529 (查看氨基酸序列)
Transcript Variant: This variant (3) lacks an alternate exon in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at a downstream start codon, compared to variant 1. The resulting protein (isoform 2) is shorter compared to isoform 1. Variants 2 and 3 encode the same protein (isoform 2).
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G112026 人 GPR161 (NM_153832) cDNA克隆 pDONR223 2ug质粒 点击询价

Upon ligand binding, G protein-coupled receptors, such as GPR161, activate cytoplasmic G proteins (see GNAS, MIM 139320), allowing the receptors to transduce extracellular signals across the plasma membrane into the cell. Phosphorylation of the receptor attenuates signaling (Matteson et al., 2008 [PubMed 18250320]).[supplied by OMIM, Aug 2008]