人 GPR161 (NM_001267614) cDNA克隆

Accession: NM_001267614
基因名称: GPR161
基因别名: RE2
基因描述: Homo sapiens G protein-coupled receptor 161 (GPR161), transcript variant 7, mRNA.
种属: Human
CDS区长度: 1248 (查看编码区序列)
翻译后氨基酸长度: 415 (查看氨基酸序列)
Transcript Variant: This variant (7) lacks a portion of the 5' coding region, initiates translation at an upstream start codon and lacks an alternate in-frame exon compared to variant 1. The resulting protein (isoform 6) is shorter and has a distinct N-terminus compared to isoform 1.
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G112032 人 GPR161 (NM_001267614) cDNA克隆 pDONR223 2ug质粒 点击询价

Upon ligand binding, G protein-coupled receptors, such as GPR161, activate cytoplasmic G proteins (see GNAS, MIM 139320), allowing the receptors to transduce extracellular signals across the plasma membrane into the cell. Phosphorylation of the receptor attenuates signaling (Matteson et al., 2008 [PubMed 18250320]).[supplied by OMIM, Aug 2008]