The protein encoded by this gene belongs to the acyltransferase family. It is located in the endoplasmic reticulum, and catalyzes the formation of fatty acid-cholesterol esters. This gene has been implicated in the formation of beta-amyloid and atherosclerotic plaques by controlling the equilibrium between free cholesterol and cytoplasmic cholesteryl esters. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2011]
人 SOAT1 (NM_003101) cDNA克隆
| Accession: | NM_003101 |
|---|---|
| 基因名称: | SOAT1 |
| 基因别名: | ACAT; SOAT; STAT; ACACT; ACAT1; ACAT-1 |
| 基因描述: | Homo sapiens sterol O-acyltransferase 1 (SOAT1), transcript variant 1, mRNA. |
| 种属: | Human |
| CDS区长度: | 1653 (查看编码区序列) |
| 翻译后氨基酸长度: | 550 (查看氨基酸序列) |
| Transcript Variant: | This variant (1) represents the predominant transcript, and encodes the longest isoform (1). |
| 人 SOAT1 (NM_003101) cDNA克隆 | transcript variant 1 |
| 人 SOAT1 (NM_001252511) cDNA克隆 | transcript variant 2 |
| 人 SOAT1 (NM_001252512) cDNA克隆 | transcript variant 3 |
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