人 SOAT1 (NM_001252512) cDNA克隆

Accession: NM_001252512
基因名称: SOAT1
基因别名: ACAT; SOAT; STAT; ACACT; ACAT1; ACAT-1
基因描述: Homo sapiens sterol O-acyltransferase 1 (SOAT1), transcript variant 3, mRNA.
种属: Human
CDS区长度: 1458 (查看编码区序列)
翻译后氨基酸长度: 485 (查看氨基酸序列)
Transcript Variant: This variant (3) lacks an internal exon in the 5' region compared to variant 1. This results in translation initiation from an in-frame, downstream start codon, and an isoform (3) with a shorter N-terminus compared to isoform 1.
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G112196 人 SOAT1 (NM_001252512) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene belongs to the acyltransferase family. It is located in the endoplasmic reticulum, and catalyzes the formation of fatty acid-cholesterol esters. This gene has been implicated in the formation of beta-amyloid and atherosclerotic plaques by controlling the equilibrium between free cholesterol and cytoplasmic cholesteryl esters. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2011]