人 MSLN (NM_005823) cDNA克隆

Accession: NM_005823
基因名称: MSLN
基因别名: MPF; SMRP
基因描述: Homo sapiens mesothelin (MSLN), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1869 (查看编码区序列)
翻译后氨基酸长度: 622 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the predominant transcript and encodes isoform 1. Both variants 1 and 3 encode the same isoform isoform (1).
产品编号 产品名称 载体 规格 价格
G112480 人 MSLN (NM_005823) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a precursor protein that is cleaved into two products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiation factor functions as a cytokine that can stimulate colony formation in bone marrow megakaryocytes. Mesothelian is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Apr 2010]