人 MSLN (NM_013404) cDNA克隆

Accession: NM_013404
基因名称: MSLN
基因别名: MPF; SMRP
基因描述: Homo sapiens mesothelin (MSLN), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1893 (查看编码区序列)
翻译后氨基酸长度: 630 (查看氨基酸序列)
Transcript Variant: This transcript variant (2) uses an alternate splice site in the coding region, compared to variant 1. Variant 2 encodes isoform 2 which is longer than isoform 1.
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G112481 人 MSLN (NM_013404) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a precursor protein that is cleaved into two products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiation factor functions as a cytokine that can stimulate colony formation in bone marrow megakaryocytes. Mesothelian is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Apr 2010]