人 PFKP (NM_002627) cDNA克隆

基本信息

Accession: NM_002627
基因名称: PFKP
基因别名: PFKF; PFK-C
基因描述: Homo sapiens phosphofructokinase, platelet (PFKP), transcript variant 1, mRNA.
种属: Human
CDS区长度: 2355 (查看编码区序列)
翻译后氨基酸长度: 784 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).

订购信息

产品编号 产品名称 载体 规格 价格
G112874 人 PFKP (NM_002627) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 PFKP (NM_002627) cDNA克隆 transcript variant 1
人 PFKP (NM_001242339) cDNA克隆 transcript variant 2

基因简介

The PFKP gene encodes the platelet isoform of phosphofructokinase (PFK) (ATP:D-fructose-6-phosphate-1-phosphotransferase, EC 2.7.1.11). PFK catalyzes the irreversible conversion of fructose-6-phosphate to fructose-1,6-bisphosphate and is a key regulatory enzyme in glycolysis. The PFKP gene, which maps to chromosome 10p, is also expressed in fibroblasts. See also the muscle (PFKM; MIM 610681) and liver (PFKL; MIM 171860) isoforms of phosphofructokinase, which map to chromosomes 12q13 and 21q22, respectively. Vora (1981) [PubMed 6451249] determined that full tetrameric phophofructokinase enzyme expressed in platelets can be composed of subunits P4, P3L, and P2L2.[supplied by OMIM, Mar 2008]

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