人 PFKP (NM_001242339) cDNA克隆

基本信息

Accession: NM_001242339
基因名称: PFKP
基因别名: PFKF; PFK-C
基因描述: Homo sapiens phosphofructokinase, platelet (PFKP), transcript variant 2, mRNA.
种属: Human
CDS区长度: 2331 (查看编码区序列)
翻译后氨基酸长度: 776 (查看氨基酸序列)
Transcript Variant: This variant (2) differs in the 5' UTR and has multiple coding region differences, compared to variant 1. These differences causes translation initiation at an alternate AUG and results an isoform (2) that is shorter and has a distinct N-terminus, compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G112875 人 PFKP (NM_001242339) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 PFKP (NM_002627) cDNA克隆 transcript variant 1
人 PFKP (NM_001242339) cDNA克隆 transcript variant 2

基因简介

The PFKP gene encodes the platelet isoform of phosphofructokinase (PFK) (ATP:D-fructose-6-phosphate-1-phosphotransferase, EC 2.7.1.11). PFK catalyzes the irreversible conversion of fructose-6-phosphate to fructose-1,6-bisphosphate and is a key regulatory enzyme in glycolysis. The PFKP gene, which maps to chromosome 10p, is also expressed in fibroblasts. See also the muscle (PFKM; MIM 610681) and liver (PFKL; MIM 171860) isoforms of phosphofructokinase, which map to chromosomes 12q13 and 21q22, respectively. Vora (1981) [PubMed 6451249] determined that full tetrameric phophofructokinase enzyme expressed in platelets can be composed of subunits P4, P3L, and P2L2.[supplied by OMIM, Mar 2008]

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