人 LMO2 (NM_001142315) cDNA克隆

基本信息

Accession: NM_001142315
基因名称: LMO2
基因别名: TTG2; RBTN2; RHOM2; RBTNL1
基因描述: Homo sapiens LIM domain only 2 (rhombotin-like 1) (LMO2), transcript variant 2, mRNA.
种属: Human
CDS区长度: 477 (查看编码区序列)
翻译后氨基酸长度: 158 (查看氨基酸序列)
Transcript Variant: This variant (2) differs in the 5' UTR and lacks a portion of the 5' coding region, compared to variant 1. These differences cause translation initiation at a downstream in-frame ATG and an isoform (2) with a shorter N-terminus, compared to isoform 1. Variants 2 and 3 encode the same isoform (2).

订购信息

产品编号 产品名称 载体 规格 价格
G113054 人 LMO2 (NM_001142315) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 LMO2 (NM_005574) cDNA克隆 transcript variant 1
人 LMO2 (NM_001142315) cDNA克隆 transcript variant 2
人 LMO2 (NM_001142316) cDNA克隆 transcript variant 3

基因简介

LMO2 encodes a cysteine-rich, two LIM-domain protein that is required for yolk sac erythropoiesis. The LMO2 protein has a central and crucial role in hematopoietic development and is highly conserved. The LMO2 transcription start site is located approximately 25 kb downstream from the 11p13 T-cell translocation cluster (11p13 ttc), where a number T-cell acute lymphoblastic leukemia-specific translocations occur. Alternative splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Nov 2008]

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