人 LMO2 (NM_005574) cDNA克隆

Accession: NM_005574
基因名称: LMO2
基因别名: TTG2; RBTN2; RHOM2; RBTNL1
基因描述: Homo sapiens LIM domain only 2 (rhombotin-like 1) (LMO2), transcript variant 1, mRNA.
种属: Human
CDS区长度: 684 (查看编码区序列)
翻译后氨基酸长度: 227 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform.
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G113056 人 LMO2 (NM_005574) cDNA克隆 pDONR223 2ug质粒 点击询价

LMO2 encodes a cysteine-rich, two LIM-domain protein that is required for yolk sac erythropoiesis. The LMO2 protein has a central and crucial role in hematopoietic development and is highly conserved. The LMO2 transcription start site is located approximately 25 kb downstream from the 11p13 T-cell translocation cluster (11p13 ttc), where a number T-cell acute lymphoblastic leukemia-specific translocations occur. Alternative splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Nov 2008]