人 CFLAR (NM_001127183) cDNA克隆

Accession: NM_001127183
基因名称: CFLAR
基因别名: CASH; FLIP; MRIT; CLARP; FLAME; Casper; FLAME1; c-FLIP; FLAME-1; I-FLICE; c-FLIPL; c-FLIPR; c-FLIPS; CASP8AP1
基因描述: Homo sapiens CASP8 and FADD-like apoptosis regulator (CFLAR), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1443 (查看编码区序列)
翻译后氨基酸长度: 480 (查看氨基酸序列)
Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 both encode the same isoform (1).
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G113457 人 CFLAR (NM_001127183) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene is a regulator of apoptosis and is structurally similar to caspase-8. However, the encoded protein lacks caspase activity and appears to be itself cleaved into two peptides by caspase-8. Several transcript variants encoding different isoforms have been found for this gene, and partial evidence for several more variants exists. [provided by RefSeq, Feb 2011]