人 CFLAR (NM_001202516) cDNA克隆

Accession: NM_001202516
基因名称: CFLAR
基因别名: CASH; FLIP; MRIT; CLARP; FLAME; Casper; FLAME1; c-FLIP; FLAME-1; I-FLICE; c-FLIPL; c-FLIPR; c-FLIPS; CASP8AP1
基因描述: Homo sapiens CASP8 and FADD-like apoptosis regulator (CFLAR), transcript variant 5, mRNA.
种属: Human
CDS区长度: 1338 (查看编码区序列)
翻译后氨基酸长度: 445 (查看氨基酸序列)
Transcript Variant: This variant (5) lacks an alternate in-frame segment compared to variant 1. The resulting isoform (4) has the same N- and C-termini but is shorter compared to isoform 1.
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G113461 人 CFLAR (NM_001202516) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene is a regulator of apoptosis and is structurally similar to caspase-8. However, the encoded protein lacks caspase activity and appears to be itself cleaved into two peptides by caspase-8. Several transcript variants encoding different isoforms have been found for this gene, and partial evidence for several more variants exists. [provided by RefSeq, Feb 2011]