人 SLCO1C1 (NM_017435) cDNA克隆

基本信息

Accession: NM_017435
基因名称: SLCO1C1
基因别名: OATP1; OATPF; OATP-F; OATP14; OATP1C1; OATPRP5; SLC21A14
基因描述: Homo sapiens solute carrier organic anion transporter family, member 1C1 (SLCO1C1), transcript variant 2, mRNA.
种属: Human
CDS区长度: 2139 (查看编码区序列)
翻译后氨基酸长度: 712 (查看氨基酸序列)
Transcript Variant: This variant (2) differs in the 5' UTR and uses an alternate splice site in the 3' coding region that results in a frameshift, compared to variant 1. The resulting protein (isoform 2) has a distinct C-terminus and is shorter than isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G113674 人 SLCO1C1 (NM_017435) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 SLCO1C1 (NM_001145946) cDNA克隆 transcript variant 1
人 SLCO1C1 (NM_017435) cDNA克隆 transcript variant 2
人 SLCO1C1 (NM_001145945) cDNA克隆 transcript variant 3
人 SLCO1C1 (NM_001145944) cDNA克隆 transcript variant 4

基因简介

This gene encodes a member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of thyroid hormones in brain tissues. This protein has particularly high affinity for the thyroid hormones thyroxine, tri-iodothyronine and reverse tri-iodothyronine. Polymorphisms in the gene encoding this protein may be associated with fatigue and depression in patients suffering from hyperthyroidism. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2009]

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