人 SLCO1C1 (NM_001145946) cDNA克隆

Accession: NM_001145946
基因名称: SLCO1C1
基因别名: OATP1; OATPF; OATP-F; OATP14; OATP1C1; OATPRP5; SLC21A14
基因描述: Homo sapiens solute carrier organic anion transporter family, member 1C1 (SLCO1C1), transcript variant 1, mRNA.
种属: Human
CDS区长度: 2193 (查看编码区序列)
翻译后氨基酸长度: 730 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
产品编号 产品名称 载体 规格 价格
G113675 人 SLCO1C1 (NM_001145946) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of thyroid hormones in brain tissues. This protein has particularly high affinity for the thyroid hormones thyroxine, tri-iodothyronine and reverse tri-iodothyronine. Polymorphisms in the gene encoding this protein may be associated with fatigue and depression in patients suffering from hyperthyroidism. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2009]