人 TKTL1 (NM_001145934) cDNA克隆

基本信息

Accession: NM_001145934
基因名称: TKTL1
基因别名: TKR; TKT2
基因描述: Homo sapiens transketolase-like 1 (TKTL1), transcript variant 3, mRNA.
种属: Human
CDS区长度: 1623 (查看编码区序列)
翻译后氨基酸长度: 540 (查看氨基酸序列)
Transcript Variant: This variant (3) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (c) has a distinct N-terminus and is shorter than isoform a.

订购信息

产品编号 产品名称 载体 规格 价格
G113711 人 TKTL1 (NM_001145934) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 TKTL1 (NM_012253) cDNA克隆 transcript variant 1
人 TKTL1 (NM_001145933) cDNA克隆 transcript variant 2
人 TKTL1 (NM_001145934) cDNA克隆 transcript variant 3

基因简介

The protein encoded by this gene is a transketolase that acts as a homodimer and catalyzes the conversion of sedoheptulose 7-phosphate and D-glyceraldehyde 3-phosphate to D-ribose 5-phosphate and D-xylulose 5-phosphate. This reaction links the pentose phosphate pathway with the glycolytic pathway. Variations in this gene may be the cause of Wernicke-Korsakoff syndrome. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]

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