人 TKTL1 (NM_012253) cDNA克隆

Accession: NM_012253
基因名称: TKTL1
基因别名: TKR; TKT2
基因描述: Homo sapiens transketolase-like 1 (TKTL1), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1791 (查看编码区序列)
翻译后氨基酸长度: 596 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a).
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G113712 人 TKTL1 (NM_012253) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene is a transketolase that acts as a homodimer and catalyzes the conversion of sedoheptulose 7-phosphate and D-glyceraldehyde 3-phosphate to D-ribose 5-phosphate and D-xylulose 5-phosphate. This reaction links the pentose phosphate pathway with the glycolytic pathway. Variations in this gene may be the cause of Wernicke-Korsakoff syndrome. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]