人 ADAM15 (NM_207191) cDNA克隆

基本信息

Accession: NM_207191
基因名称: ADAM15
基因别名: MDC15
基因描述: Homo sapiens ADAM metallopeptidase domain 15 (ADAM15), transcript variant 1, mRNA.
种属: Human
CDS区长度: 2319 (查看编码区序列)
翻译后氨基酸长度: 772 (查看氨基酸序列)
Transcript Variant: This variant (1) lacks three exons in the coding region compared to variant 6, one of which causes a translation frameshift. The resulting isoform (1) has a distinct and shorter C-terminus, as compared to the longest isoform (6).

订购信息

产品编号 产品名称 载体 规格 价格
G113767 人 ADAM15 (NM_207191) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 ADAM15 (NM_207191) cDNA克隆 transcript variant 1
人 ADAM15 (NM_003815) cDNA克隆 transcript variant 2
人 ADAM15 (NM_207194) cDNA克隆 transcript variant 3
人 ADAM15 (NM_207195) cDNA克隆 transcript variant 4
人 ADAM15 (NM_207196) cDNA克隆 transcript variant 5
人 ADAM15 (NM_207197) cDNA克隆 transcript variant 6
人 ADAM15 (NM_001261464) cDNA克隆 transcript variant 7
人 ADAM15 (NM_001261465) cDNA克隆 transcript variant 8
人 ADAM15 (NM_001261466) cDNA克隆 transcript variant 9

基因简介

The protein encoded by this gene is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, this protein specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]

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