人 ADAM15 (NM_001261466) cDNA克隆

基本信息

Accession: NM_001261466
基因名称: ADAM15
基因别名: MDC15
基因描述: Homo sapiens ADAM metallopeptidase domain 15 (ADAM15), transcript variant 9, mRNA.
种属: Human
CDS区长度: 1902 (查看编码区序列)
翻译后氨基酸长度: 633 (查看氨基酸序列)
Transcript Variant: This variant (9) has multiple differences in the 5' coding region and differs in the 3' coding region and UTR compared to variant 6. The resulting protein (isoform 9) is shorter and has a distinct C-terminus compared to isoform 6.

订购信息

产品编号 产品名称 载体 规格 价格
G113774 人 ADAM15 (NM_001261466) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 ADAM15 (NM_207191) cDNA克隆 transcript variant 1
人 ADAM15 (NM_003815) cDNA克隆 transcript variant 2
人 ADAM15 (NM_207194) cDNA克隆 transcript variant 3
人 ADAM15 (NM_207195) cDNA克隆 transcript variant 4
人 ADAM15 (NM_207196) cDNA克隆 transcript variant 5
人 ADAM15 (NM_207197) cDNA克隆 transcript variant 6
人 ADAM15 (NM_001261464) cDNA克隆 transcript variant 7
人 ADAM15 (NM_001261465) cDNA克隆 transcript variant 8
人 ADAM15 (NM_001261466) cDNA克隆 transcript variant 9

基因简介

The protein encoded by this gene is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, this protein specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]

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