人 ADAM2 (NM_001278113) cDNA克隆

Accession: NM_001278113
基因名称: ADAM2
基因别名: CT15; FTNB; PH30; CRYN1; CRYN2; PH-30b; PH30-beta
基因描述: Homo sapiens ADAM metallopeptidase domain 2 (ADAM2), transcript variant 2, mRNA.
种属: Human
CDS区长度: 2151 (查看编码区序列)
翻译后氨基酸长度: 716 (查看氨基酸序列)
Transcript Variant: This variant (2) lacks an internal in-frame exon in the coding region, compared to variant 1. The encoded isoform (2) is shorter, compared to isoform 1.
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G113817 人 ADAM2 (NM_001278113) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The encoded protein is a subunit of an integral sperm membrane glycoprotein called fertilin, which plays an important role in sperm-egg interactions. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013]