人 GLI1 (NM_001160045) cDNA克隆

基本信息

Accession: NM_001160045
基因名称: GLI1
基因别名: GLI
基因描述: Homo sapiens GLI family zinc finger 1 (GLI1), transcript variant 2, mRNA.
种属: Human
CDS区长度: 2937 (查看编码区序列)
翻译后氨基酸长度: 978 (查看氨基酸序列)
Transcript Variant: This variant (1) omits the first two coding exons, compared to variant 1, resulting in transcription initiation from an internal AUG site and a N-terminally truncated protein isoform (2), also know as GLI1DeltaN. This variant reflects the transcript and protein described by Shimokawa (PubMed ID 18378682).

订购信息

产品编号 产品名称 载体 规格 价格
G113999 人 GLI1 (NM_001160045) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 GLI1 (NM_005269) cDNA克隆 transcript variant 1
人 GLI1 (NM_001160045) cDNA克隆 transcript variant 2
人 GLI1 (NM_001167609) cDNA克隆 transcript variant 3

基因简介

This gene encodes a member of the Kruppel family of zinc finger proteins. The encoded transcription factor is activated by the sonic hedgehog signal transduction cascade and regulates stem cell proliferation. The activity and nuclear localization of this protein is negatively regulated by p53 in an inhibitory loop. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]

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