人 GLI1 (NM_005269) cDNA克隆

Accession: NM_005269
基因名称: GLI1
基因别名: GLI
基因描述: Homo sapiens GLI family zinc finger 1 (GLI1), transcript variant 1, mRNA.
种属: Human
CDS区长度: 3321 (查看编码区序列)
翻译后氨基酸长度: 1106 (查看氨基酸序列)
Transcript Variant: This variant (1) encodes the full length protein (isoform 1).
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G114000 人 GLI1 (NM_005269) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a member of the Kruppel family of zinc finger proteins. The encoded transcription factor is activated by the sonic hedgehog signal transduction cascade and regulates stem cell proliferation. The activity and nuclear localization of this protein is negatively regulated by p53 in an inhibitory loop. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]