人 CAST (NM_173060) cDNA克隆

基本信息

Accession: NM_173060
基因名称: CAST
基因别名: BS-17
基因描述: Homo sapiens calpastatin (CAST), transcript variant 2, mRNA.
种属: Human
CDS区长度: 2061 (查看编码区序列)
翻译后氨基酸长度: 686 (查看氨基酸序列)
Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at a downstream start codon, compared to variant 6. This variant also contains an in-frame exon compared to variant 6. The encoded isoform (b) is shorter than isoform f.

订购信息

产品编号 产品名称 载体 规格 价格
G115162 人 CAST (NM_173060) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 CAST (NM_001190442) cDNA克隆 transcript variant 11
人 CAST (NM_001284212) cDNA克隆 transcript variant 13
人 CAST (NM_001284213) cDNA克隆 transcript variant 14
人 CAST (NM_173060) cDNA克隆 transcript variant 2
人 CAST (NM_001042440) cDNA克隆 transcript variant 6

基因简介

The protein encoded by this gene is an endogenous calpain (calcium-dependent cysteine protease) inhibitor. It consists of an N-terminal domain L and four repetitive calpain-inhibition domains (domains 1-4), and it is involved in the proteolysis of amyloid precursor protein. The calpain/calpastatin system is involved in numerous membrane fusion events, such as neural vesicle exocytosis and platelet and red-cell aggregation. The encoded protein is also thought to affect the expression levels of genes encoding structural or regulatory proteins. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jun 2010]

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