人 CAST (NM_001284213) cDNA克隆

基本信息

Accession: NM_001284213
基因名称: CAST
基因别名: BS-17
基因描述: Homo sapiens calpastatin (CAST), transcript variant 14, mRNA.
种属: Human
CDS区长度: 1911 (查看编码区序列)
翻译后氨基酸长度: 636 (查看氨基酸序列)
Transcript Variant: This variant (14) has multiple differences but maintains the reading frame, compared to variant 1. This variant encodes isoform o, which is shorter than isoform f.

订购信息

产品编号 产品名称 载体 规格 价格
G115166 人 CAST (NM_001284213) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 CAST (NM_001190442) cDNA克隆 transcript variant 11
人 CAST (NM_001284212) cDNA克隆 transcript variant 13
人 CAST (NM_001284213) cDNA克隆 transcript variant 14
人 CAST (NM_173060) cDNA克隆 transcript variant 2
人 CAST (NM_001042440) cDNA克隆 transcript variant 6

基因简介

The protein encoded by this gene is an endogenous calpain (calcium-dependent cysteine protease) inhibitor. It consists of an N-terminal domain L and four repetitive calpain-inhibition domains (domains 1-4), and it is involved in the proteolysis of amyloid precursor protein. The calpain/calpastatin system is involved in numerous membrane fusion events, such as neural vesicle exocytosis and platelet and red-cell aggregation. The encoded protein is also thought to affect the expression levels of genes encoding structural or regulatory proteins. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jun 2010]

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