人 HDAC8 (NM_001166448) cDNA克隆

基本信息

Accession: NM_001166448
基因名称: HDAC8
基因别名: HD8; WTS; RPD3; CDA07; CDLS5; MRXS6; HDACL1
基因描述: Homo sapiens histone deacetylase 8 (HDAC8), transcript variant 6, mRNA.
种属: Human
CDS区长度: 420 (查看编码区序列)
翻译后氨基酸长度: 139 (查看氨基酸序列)
Transcript Variant: This variant (6) lacks multiple alternate coding exons and uses an alternate 3' terminal exon, compared to variant 1. The encoded isoform (3) maintains the reading frame, but is shorter and has a distinct C-terminus, compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G116704 人 HDAC8 (NM_001166448) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 HDAC8 (NM_018486) cDNA克隆 transcript variant 1
人 HDAC8 (NM_001166418) cDNA克隆 transcript variant 2
人 HDAC8 (NM_001166419) cDNA克隆 transcript variant 3
人 HDAC8 (NM_001166420) cDNA克隆 transcript variant 4
人 HDAC8 (NM_001166422) cDNA克隆 transcript variant 5
人 HDAC8 (NM_001166448) cDNA克隆 transcript variant 6

基因简介

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]

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