人 HDAC8 (NM_018486) cDNA克隆

Accession: NM_018486
基因名称: HDAC8
基因别名: HD8; WTS; RPD3; CDA07; CDLS5; MRXS6; HDACL1
基因描述: Homo sapiens histone deacetylase 8 (HDAC8), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1134 (查看编码区序列)
翻译后氨基酸长度: 377 (查看氨基酸序列)
Transcript Variant: This variant (1) encodes the longest isoform (1).
产品编号 产品名称 载体 规格 价格
G116705 人 HDAC8 (NM_018486) cDNA克隆 pDONR223 2ug质粒 点击询价

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]