人 ORC6 (NM_014321) cDNA克隆

Accession: NM_014321
基因名称: ORC6
基因别名: ORC6L
基因描述: Homo sapiens origin recognition complex, subunit 6 (ORC6), transcript variant 1, mRNA.
种属: Human
CDS区长度: 759 (查看编码区序列)
翻译后氨基酸长度: 252 (查看氨基酸序列)
Transcript Variant: This variant (1) encodes the functional protein.
产品编号 产品名称 载体 规格 价格
G117138 人 ORC6 (NM_014321) cDNA克隆 pDONR223 2ug质粒 点击询价

The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. Gene silencing studies with small interfering RNA demonstrated that this protein plays an essential role in coordinating chromosome replication and segregation with cytokinesis. [provided by RefSeq, Oct 2010]