人 ORC3 (NM_001197259) cDNA克隆

基本信息

Accession: NM_001197259
基因名称: ORC3
基因别名: LAT; ORC3L; LATHEO
基因描述: Homo sapiens origin recognition complex, subunit 3 (ORC3), transcript variant 3, mRNA.
种属: Human
CDS区长度: 1707 (查看编码区序列)
翻译后氨基酸长度: 568 (查看氨基酸序列)
Transcript Variant: This variant (3) lacks an exon in the 5' coding region, resulting in a downstream AUG start codon, and also lacks three nts in an alternate splicing site in the 3' coding region, as compared to variant 1. The translation reading frame remains the same, and the resulting isoform (3) has a shorter N-terminus and lacks an internal aa, as compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G119580 人 ORC3 (NM_001197259) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 ORC3 (NM_181837) cDNA克隆 transcript variant 1
人 ORC3 (NM_012381) cDNA克隆 transcript variant 2
人 ORC3 (NM_001197259) cDNA克隆 transcript variant 3

基因简介

The origin recognition complex (ORC) is a highly conserved six subunits protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. Studies of a similar gene in Drosophila suggested a possible role of this protein in neuronal proliferation and olfactory memory. Alternatively spliced transcript variants encoding distinct isoforms have been reported for this gene. [provided by RefSeq, Jul 2008]

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