人 RBBP5 (NM_001193272) cDNA克隆

Accession: NM_001193272
基因名称: RBBP5
基因别名: RBQ3; SWD1
基因描述: Homo sapiens retinoblastoma binding protein 5 (RBBP5), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1503 (查看编码区序列)
翻译后氨基酸长度: 500 (查看氨基酸序列)
Transcript Variant: This variant (2) uses a different splice site in the 3' coding region, compared to variant 1. The resulting protein (isoform 2) is shorter when it is compared to isoform 1.
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G117453 人 RBBP5 (NM_001193272) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a ubiquitously expressed nuclear protein which belongs to a highly conserved subfamily of WD-repeat proteins. The encoded protein binds directly to retinoblastoma protein, which regulates cell proliferation. It interacts preferentially with the underphosphorylated retinoblastoma protein via the E1A-binding pocket B. Three alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Jul 2010]