人 NEIL2 (NM_001135747) cDNA克隆

基本信息

Accession: NM_001135747
基因名称: NEIL2
基因别名: NEH2; NEI2
基因描述: Homo sapiens nei endonuclease VIII-like 2 (E. coli) (NEIL2), transcript variant 3, mRNA.
种属: Human
CDS区长度: 816 (查看编码区序列)
翻译后氨基酸长度: 271 (查看氨基酸序列)
Transcript Variant: This variant (3) differs in the 5' UTR, uses an alternate splice site at the end of an exon, and lacks an alternate exon compared to variant 1. The resulting isoform (b) has the same N- and C-termini but is shorter compared to isoform a.

订购信息

产品编号 产品名称 载体 规格 价格
G117782 人 NEIL2 (NM_001135747) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 NEIL2 (NM_145043) cDNA克隆 transcript variant 1
人 NEIL2 (NM_001135746) cDNA克隆 transcript variant 2
人 NEIL2 (NM_001135747) cDNA克隆 transcript variant 3
人 NEIL2 (NM_001135748) cDNA克隆 transcript variant 4

基因简介

NEIL2 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction (Bandaru et al., 2002 [PubMed 12509226])[supplied by OMIM, Mar 2008]

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