人 NEIL2 (NM_001135748) cDNA克隆

基本信息

Accession: NM_001135748
基因名称: NEIL2
基因别名: NEH2; NEI2
基因描述: Homo sapiens nei endonuclease VIII-like 2 (E. coli) (NEIL2), transcript variant 4, mRNA.
种属: Human
CDS区长度: 651 (查看编码区序列)
翻译后氨基酸长度: 216 (查看氨基酸序列)
Transcript Variant: This variant (4) differs in the 5' UTR and lacks an alternate exon compared to variant 1. The resulting isoform (c) is shorter at the N-terminus compared to isoform a.

订购信息

产品编号 产品名称 载体 规格 价格
G117783 人 NEIL2 (NM_001135748) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 NEIL2 (NM_145043) cDNA克隆 transcript variant 1
人 NEIL2 (NM_001135746) cDNA克隆 transcript variant 2
人 NEIL2 (NM_001135747) cDNA克隆 transcript variant 3
人 NEIL2 (NM_001135748) cDNA克隆 transcript variant 4

基因简介

NEIL2 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction (Bandaru et al., 2002 [PubMed 12509226])[supplied by OMIM, Mar 2008]

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