人 APH1B (NM_001145646) cDNA克隆

基本信息

Accession: NM_001145646
基因名称: APH1B
基因别名: PSFL; APH-1B; PRO1328; TAAV688
基因描述: Homo sapiens APH1B gamma secretase subunit (APH1B), transcript variant 2, mRNA.
种属: Human
CDS区长度: 651 (查看编码区序列)
翻译后氨基酸长度: 216 (查看氨基酸序列)
Transcript Variant: This variant (2) lacks an in-frame coding exon and encodes a shorter isoform (2), as compared to variant 1.

订购信息

产品编号 产品名称 载体 规格 价格
G118680 人 APH1B (NM_001145646) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 APH1B (NM_031301) cDNA克隆 transcript variant 1
人 APH1B (NM_001145646) cDNA克隆 transcript variant 2

基因简介

This gene encodes a multi-pass transmembrane protein that is a functional component of the gamma-secretase complex, which also contains presenilin and nicastrin. This protein represents a stabilizing cofactor for the presenilin holoprotein in the complex. The gamma-secretase complex catalyzes the cleavage of integral proteins such as notch receptors and beta-amyloid precursor protein. [provided by RefSeq, Sep 2011]

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