人 APH1B (NM_031301) cDNA克隆

Accession: NM_031301
基因名称: APH1B
基因别名: PSFL; APH-1B; PRO1328; TAAV688
基因描述: Homo sapiens APH1B gamma secretase subunit (APH1B), transcript variant 1, mRNA.
种属: Human
CDS区长度: 774 (查看编码区序列)
翻译后氨基酸长度: 257 (查看氨基酸序列)
Transcript Variant: This variant (1) encodes the longer isoform (1).
产品编号 产品名称 载体 规格 价格
G118681 人 APH1B (NM_031301) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a multi-pass transmembrane protein that is a functional component of the gamma-secretase complex, which also contains presenilin and nicastrin. This protein represents a stabilizing cofactor for the presenilin holoprotein in the complex. The gamma-secretase complex catalyzes the cleavage of integral proteins such as notch receptors and beta-amyloid precursor protein. [provided by RefSeq, Sep 2011]