人 KCNMB2 (NM_181361) cDNA克隆

Accession: NM_181361
基因名称: KCNMB2
基因描述: Homo sapiens potassium large conductance calcium-activated channel, subfamily M, beta member 2 (KCNMB2), transcript variant 1, mRNA.
种属: Human
CDS区长度: 708 (查看编码区序列)
翻译后氨基酸长度: 235 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longest transcript. Variants 1, 2 and 3 encode the same protein.
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G118726 人 KCNMB2 (NM_181361) cDNA克隆 pDONR223 2ug质粒 点击询价

MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is an auxiliary beta subunit which decreases the activation time of MaxiK alpha subunit currents. Alternative splicing results in multiple transcript variants of this gene. Additional variants are discussed in the literature, but their full length nature has not been described. [provided by RefSeq, Jul 2013]