人 KCNMB3 (NM_171828) cDNA克隆

Accession: NM_171828
基因名称: KCNMB3
基因别名: HBETA3; KCNMB2; KCNMBL; BKBETA3; SLOBETA3
基因描述: Homo sapiens potassium large conductance calcium-activated channel, subfamily M beta member 3 (KCNMB3), transcript variant 1, mRNA.
种属: Human
CDS区长度: 834 (查看编码区序列)
翻译后氨基酸长度: 277 (查看氨基酸序列)
Transcript Variant: This variant (1) differs in the 5' UTR and 5' coding region, and uses an alternate translational start codon, compared to variant 4. The resulting isoform (a) has a distinct N-terminus and is shorter than isoform d.
产品编号 产品名称 载体 规格 价格
G144998 人 KCNMB3 (NM_171828) cDNA克隆 pDONR223 2ug质粒 点击询价

MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is an auxiliary beta subunit which may partially inactivate or slightly decrease the activation time of MaxiK alpha subunit currents. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 22. [provided by RefSeq, Jul 2009]