人 KNG1 (NM_001102416) cDNA克隆

Accession: NM_001102416
基因名称: KNG1
基因别名: BK; BDK; KNG
基因描述: Homo sapiens kininogen 1 (KNG1), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1935 (查看编码区序列)
翻译后氨基酸长度: 644 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1), also known as high molecular weight preprokininogen.
产品编号 产品名称 载体 规格 价格
G119005 人 KNG1 (NM_001102416) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene uses alternative splicing to generate two different proteins- high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, bradykinin, a peptide causing numerous physiological effects, is released from HMWK. In contrast to HMWK, LMWK is not involved in blood coagulation. Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009]