人 KNG1 (NM_000893) cDNA克隆

基本信息

Accession: NM_000893
基因名称: KNG1
基因别名: BK; BDK; KNG
基因描述: Homo sapiens kininogen 1 (KNG1), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1284 (查看编码区序列)
翻译后氨基酸长度: 427 (查看氨基酸序列)
Transcript Variant: This variant (2) uses an alternate splice pattern in the 3' coding region, compared to variant 1. The resulting isoform (2), also known as low molecular weight preprokininogen, has a shorter and distinct C-terminus, compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G119006 人 KNG1 (NM_000893) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 KNG1 (NM_001102416) cDNA克隆 transcript variant 1
人 KNG1 (NM_000893) cDNA克隆 transcript variant 2
人 KNG1 (NM_001166451) cDNA克隆 transcript variant 3

基因简介

This gene uses alternative splicing to generate two different proteins- high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, bradykinin, a peptide causing numerous physiological effects, is released from HMWK. In contrast to HMWK, LMWK is not involved in blood coagulation. Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009]

相关产品