人 RFC1 (NM_002913) cDNA克隆

Accession: NM_002913
基因名称: RFC1
基因别名: A1; RFC; PO-GA; RECC1; MHCBFB; RFC140
基因描述: Homo sapiens replication factor C (activator 1) 1, 145kDa (RFC1), transcript variant 1, mRNA.
种属: Human
CDS区长度: 3444 (查看编码区序列)
翻译后氨基酸长度: 1147 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the predominant transcript, and encodes isoform 1.
产品编号 产品名称 载体 规格 价格
G120033 人 RFC1 (NM_002913) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes the large subunit of replication factor C, a five subunit DNA polymerase accessory protein, which is a DNA-dependent ATPase required for eukaryotic DNA replication and repair. The large subunit acts as an activator of DNA polymerases, binds to the 3' end of primers, and promotes coordinated synthesis of both strands. It may also have a role in telomere stability. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Mar 2011]