人 RFC2 (NM_001278791) cDNA克隆

基本信息

Accession: NM_001278791
基因名称: RFC2
基因别名: RFC40
基因描述: Homo sapiens replication factor C (activator 1) 2, 40kDa (RFC2), transcript variant 3, mRNA.
种属: Human
CDS区长度: 762 (查看编码区序列)
翻译后氨基酸长度: 253 (查看氨基酸序列)
Transcript Variant: This variant (3) uses an alternate splice site in its 5' UTR, and initiates translation at a downstream start codon, compared to variant 1. The encoded isoform (3) has a shorter N-terminus, compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G157094 人 RFC2 (NM_001278791) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 RFC2 (NM_181471) cDNA克隆 transcript variant 1
人 RFC2 (NM_002914) cDNA克隆 transcript variant 2
人 RFC2 (NM_001278791) cDNA克隆 transcript variant 3
人 RFC2 (NM_001278792) cDNA克隆 transcript variant 4
人 RFC2 (NM_001278793) cDNA克隆 transcript variant 5

基因简介

This gene encodes a member of the activator 1 small subunits family. The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins, proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). Replication factor C, also called activator 1, is a protein complex consisting of five distinct subunits. This gene encodes the 40 kD subunit, which has been shown to be responsible for binding ATP and may help promote cell survival. Disruption of this gene is associated with Williams syndrome. Alternatively spliced transcript variants encoding distinct isoforms have been described. A pseudogene of this gene has been defined on chromosome 2. [provided by RefSeq, Jul 2013]

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